Intoxicacion letal por inhalacion accidental de fosfuro alum´ inico

Fatal poisoning by accidental inhalation of aluminium phosphide Abstract The cases of two 6 and 9-year-old sisters with lethal poisoning by inhalation of aluminium phosphide, after its inadequate use in a rural environment, are described. The clinical symptoms consisted of sudden vomiting, cardiac arrhythmias, shock, dyspnea, pulmonary edema/acute respiratory distress, metabolic acidosis and hepatic dysfunction, and the patients died in spite of advanced life support. Although an early diagnosis might theoretically improve the poisoning outcome, its high lethality rate and the absence of a specific antidote, efforts must be directed towards prevention and restricting its use as pesticide and being aware of its toxicity. & 2009 Asociacion Espanola de Pediatr´ ia. Published by Elsevier Espana, S.L. All rights reserved.