MRI Demonstration of a Reversible Lesion in Cerebral Deep White Matter in Thrombotic Thrombocytopenic Purpura

We report a 75-year-old woman with thrombotic thrombocytopenic purpura (TTP) whose MRI showed diffuse abnormal signal in the deep white matter. She was successfully treated, and this abnormal signal disappeared. This finding indicates that the deep white matter is involved in TTP; the lesion may reflect reversible microangiopathy and brain oedema.