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Application of random matrix theory to biological networks

Physics Letters A, no. 6 (2006): 420-423

Cited: 121|Views33
WOS SCOPUS

Abstract

We show that spectral fluctuation of interaction matrices of a yeast protein–protein interaction network and a yeast metabolic network follows the description of the Gaussian orthogonal ensemble (GOE) of random matrix theory (RMT). Furthermore, we demonstrate that while the global biological networks evaluated belong to GOE, removal of in...More

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