Complete and unambiguous assignments of¹H and¹³C chemical shifts of new arylamino derivatives ofortho-naphthofuranquinones

Six new nor-beta-lapachones have been synthesized from reaction of 3-bromo-nor-beta-lapachone with arylamines. These derivatives have potent anticancer properties against several cell lines. Here, we report complete unambiguous assignments of H-1 and C-13 chemical shifts of the new compounds. The assignments were made using a combination of one- and two-dimensional NMR techniques (H-1, C-13, H-1-H-1 COSY, H-1-C-13 HSQC, and H-1-C-13 HMBC). Copyright (C) 2008 John Wiley & Sons, Ltd.