Synthesis and structural–activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents

Bioorganic & Medicinal Chemistry Letters（2004）

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摘要

The synthesis and SAR of the 3-hydroxyquinazoline diones, a novel class of bacterial topoisomerase inhibitors, is reported.

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关键词

3-Hydroxyquinazoline-2,4-diones,Antibacterial agents,Bacterial topoisomerase inhibitors

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