Discovery of novel and selective tertiary alcohol containing inhibitors of the norepinephrine transporter

Bioorganic & Medicinal Chemistry Letters（2006）

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摘要

An efficient synthetic route to novel norepinephrine reuptake inhibitors, their in vitro binding affinity and selected in vivo data are presented.

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关键词

Depression,Atomoxetine,Attention deficit hyperactivity disorder,ADHD,Norepinephrine,Serotonin,Dopamine,Reuptake,Inhibitor,Selective norepinephrine reuptake inhibitor,α-MMT,Metariminol,Morpholine,Tertiary alcohol

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