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The rapid evolution of signal peptides is mainly caused by relaxed selection on non-synonymous and synonymous sites.

Gene, no. 1 (2009): 8-11

被引用26|浏览6
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The precursor of a secretory protein usually contains an N-terminal signal peptide (SP), which directs the protein to cross the membrane. We performed a genome-wide analysis of secretory proteins in prokaryotes and eukaryotes, and found that signal peptides evolved faster than mature proteins. To determine whether the evolutionary pattern...更多

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