Effect of orthophosphate on versicolorin synthesis by a mutant strain ofAspergillus parasiticus
Experimental Mycology(1987)
摘要
Biosynthesis of the polyketide versicolorin A by mycelia ofAspergillus parasiticus ATCC 36537 is stimulated fourfold by raising the initial phosphate concentration of the culture medium from 0.4 to 0.8 mM. Under these conditions the total phosphate content of the mycelium remains constant at 110 μmol/g, dry weight. Increasing the phosphate concentration of the medium above 5 mM results in accumulation of phosphate by the mycelia, without further stimulation of versicolorin synthesis. In order to be efficacious in stimulating versicolorin synthesis, phosphate must be added not later than 30 h after conidial inoculation.
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关键词
Aspergillus parasiticus,versicolorin,aflatoxin,phosphate stimulation
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