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Distribution of gacyclidine enantiomers after experimental spinal cord injury in rats: possible involvement of an active transport system.

Journal of Pharmaceutical Sciences, no. 1 (2001): 70-78

Cited by: 4|Views2
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Abstract

The pharmacokinetics of gacyclidine enantiomers, a noncompetitive N‐methyl‐d‐aspartate (NMDA) antagonist, were studied in plasma and spinal cord extracellular fluid (ECF) after experimental spinal cord injury in rats. Spinal cord trauma was produced by introducing an inflatable balloon in the dorsal subdural space. Upon implantation of mi...More

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