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Metal ions protect DNA against strand breakage induced by fast neutrons.

International journal of radiation biology, no. 6 (1992): 659-666

Cited by: 32|Views4
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Single and double strand breaks (SSB and DSB) are induced by fast neutrons in plasmid (pBR322) DNA in 1 mM potassium phosphate buffer (pH 7.25). Increasing the concentration of monovalent (Na+, Cs+, Li+), divalent (Mg2+, Ca2+) and trivalent (Al3+, Co3+ (NH3)6) metal cations strongly decreases the yield of DSB. The extent of the observed p...More

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