Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents
Bioorganic & Medicinal Chemistry Letters(2009)
摘要
Efficacious gap-junction modifiers that re-establish intercellular communications and delay time to cardiac conduction block in mice treated with intravenous CaCl2 are reported.
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关键词
Gap-junction,AF,Atrial fibrillation,VT,Ventricular tachycardia,Antiarrhythmic peptide,Antiarrhythmic agent
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