Cotrafficking of SV2 and synaptotagmin at the synapse

JOURNAL OF NEUROSCIENCE, pp. 5569-5578, 2010.

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Abstract:

Synaptic vesicles are specialized cycling endosomes that contain a unique constellation of membrane proteins. Proteins are sorted to vesicles by short amino acid sequences that serve as binding sites for clathrin adaptor proteins. Here we show that a tyrosine-based endocytosis motif in the vesicle protein SV2 is required for trafficking t...More

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