Computational protein design as an optimization problem

Artificial Intelligence, pp. 59-79, 2014.

Cited by: 44|Bibtex|Views25|DOI:https://doi.org/10.1016/j.artint.2014.03.005
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Other Links: dblp.uni-trier.de|academic.microsoft.com|www.sciencedirect.com

Abstract:

Proteins are chains of simple molecules called amino acids. The three-dimensional shape of a protein and its amino acid composition define its biological function. Over millions of years, living organisms have evolved a large catalog of proteins. By exploring the space of possible amino acid sequences, protein engineering aims at similarl...More

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