Pentacyclic triterpenoids and ceramide mediate the vasorelaxant activity of Vitex cienkowskii via involvement of NO/cGMP pathway in isolated rat aortic rings

Alain Bertrand Dongmo,Anatole Guy Blaise Azebaze,Flaure Metchi Donfack,Théophile Dimo,Pepin Alango Nkeng-Efouet,Krishna Prasad Devkota,Bruno Sontia,Hildebert Wagner,Norbert Sewald,Wolfgang Vierling

Journal of Ethnopharmacology（2011）

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摘要

The aim of this study was to evaluate the vasorelaxant activity of extract and isolated compounds from Vitex cienkowskii used traditionally in Cameroon to treat cardiovascular diseases including hypertension.

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关键词

NO,L-NAME,DPPH,TLC,ODQ,SQ22536

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