Distribution and drug resistance of Acinetobacter baumannii and Pseudomonas aeruginosa in ICUs.

Objective To explore the distribution and drug resistance of Acinetobacter baumannii(ABA) and Pseudomonas aeruginosa(PAE) in intensive care units(ICUs).Method Clinical data of nosocomial infection with ABA and PAE isolates from July 2006 to June 2010 were investigated retrospectively.The results of susceptibility test against 111 ABA and 73 PAE strains were analyzed statistically.The antimicrobial susceptibility data was analyzed by WHONET 5.5 software.Result The ABA and PAE strains were mostly isolated from respiratory tract(76.1%),followed by the CVP catheter tip(8.7%).The resistant rates of ABA to eight testing drugs were more than 85%.The resistant rates to imipenem were 70.3%.Cefoperazone-Sulbactam was the only agent to which the bacteria showed the lowest resistance rate(17.1%);The resistance rates of PAE to Ticarcillin and Imipenem were 45.2% and 41.1%.The resistant rates to other testing drugs were lower than 25%.Conclusion The lower respiratory tracts are the main infection site.Most of the pathogens in intensive care units are ABA and PAE.The resistant rate of ABA and MDR-AB are more serious than tjat pf PAE.