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Synergistic Effects of Mutations and Nanoparticle Templating in the Self-Assembly of Cowpea Chlorotic Mottle Virus Capsids

NANO LETTERS, no. 1 (2009): 393-398

Cited by: 55|Views8
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Abstract

A study of the in vitro nanoparticle-templated assembly of a mutant of cowpea chlorotic mottle virus lacking most of the N-terminal domain (residues 4-37), N Delta 34, is presented. Mutant empty proteins assemble into empty capsids with a much broader distribution of sizes than the wild-type virus. This increased flexibility in the assemb...More

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