X-ray diffraction studiesof an anti-azophenylarsonate antibody and of an antigen-antibody complex

Annales de l'Institut Pasteur / Immunologie(1985)

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摘要
X-ray crystallographic studies of the Fab fragments of two murinemonoclonal antibodies of predefined specificity are under way. Diffracted X-ray intensities of the crystalline native Fab fragment of an anti-azophenylarsonate antibody and of three heavy atom derivatives have been measured to a resolution of 3.5 Å. A preliminary 6-Å resolution electron density map has been obtained.
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关键词
Arsonate,Lysozyme,Antigen-antibody complex,Three-dimensional structure,Monoclonal antibodies,Fab,Electron density map
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