Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.
Bioorganic & Medicinal Chemistry Letters（2011）
摘要
Selective, low intrinsic activity 5-HT3 receptor partial agonists with good oral activity are described.
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关键词
5-HT3 receptor partial agonist,Irritable bowel syndrome,IBS,Ligand-gated ion channel,Ramosetron,Alosetron,Indole,Indazole
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