Metastasiertes Mammakarzinom: Keine Lebensverlängerung seit 20 Jahren

Summary Metastasized breast cancer: no improvement of life expectancy in the past two decades Whether treatment of advanced metastasi- zed cancer has led to substantial improve- ment of survival in the last 20 years, is discus- sed controversially. Results of the Munich Cancer Registry in metastasized breast cancer are presented in detail. Multivariate analysis emonstrates that survival after metastases is significantly related to age, grade, receptor status and survival time without metastases. In contrast survival has not been influenced by time of diagnosis of the primary tumour or of the metastasis and of the treating insti- tution in 20 years. The literature displays sur- vival rates after metastases with only remote variation over the past 40 years. The treat- ment results are comparable with the litera- ture. In addition the benefit of mammo- graphy screening and adjuvant treatment can be demonstrated convincingly with the same data source.