Studies on the Retention and Separation Mechanisms of Phenylsuccinic Acid Enantiomers with HP-β-CD as Chrial Mobile Phase Additive in HPLC

Journal of Instrumental Analysis, pp. 39-44, 2009.

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Keywords:
chiral mobile phase additivephenylsuccinic acid enantiomerHP-β-CDRP-HPLCseparation mechanismMore(1+)

Abstract:

The chromatographic retention mechanism of phenylsuccinic acid(PSA) has been studied by reverse phase high performance liquid chromatography(RP-HPLC) with hydroxypropyl-β-cyclodextrin(HP-β-CD) as chiral mobile phase additive.The optimum chromatographic conditions for baseline separation of PSA were found to be as follows:mobile phase:10 m...More

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ZHHP-β-CD对苯基琥珀酸对映体色谱保留机制及拆分机理的研究
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