LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA

Genome research, Volume 13, Issue 4, 2003, Pages 721-731.

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摘要

To compare entire genomes from different species, biologists increasingly need alignment methods that are efficient enough to handle long sequences, and accurate enough to correctly align the conserved biological features between distant species. We present LAGAN, a system for rapid global alignment of two homologous genomic sequences, an...更多

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