Renal outcome and monoclonal immunoglobulin deposition disease in 289 old patients with blood cell dyscrasias: a single center experience.

Piero Stratta,Luciana Gravellone,Tiziana Cena,Davide Rossi,Gianluca Gaidano,Roberta Fenoglio,Elisa Lazzarich,Marco Quaglia,Andrea Airoldi,Cristina Bozzola,Guido Monga,Guido Valente,Caterina Canavese,Corrado Magnani

Critical Reviews in Oncology/Hematology（2011）

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摘要

Monoclonal components (MC) formed by chains/fragments of intact/truncated globulin components produced in different lymphoproliferative diseases are responsible for monoclonal immunoglobulin deposition disease (MIDD) and consequent tissue damage by organized (amyloid fibrils) or non-organized (amorphous) deposits.

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关键词

Paraproteinemia,Monoclonal immunoglobulin deposition disease,Elderly patients,Myeloma,Monoclonal component,Glomerular proteinuria,Albuminuria,Bence Jones proteinuria,Renal failure,Diabetes

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