Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.
Bioorganic & Medicinal Chemistry（2009）
摘要
The identification of highly potent and orally available Y5 receptor antagonist, spiroindoline-3,4′-piperidine 3a, was reported.
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关键词
NPY,Neuropeptide Y,Y5 receptor,Spiroindoline,Obesity,Phenyl imidazole
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