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Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression.

Acta biochimica et biophysica Sinica, no. 7 (2010): 496-501

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The aberrant activation of c-Src regulates multiple functions during tumor progression. This study was conducted to investigate the role of c-Src suppression in epithelial to mesenchymal transition (EMT) process in human breast carcinoma cells. c-Src suppression by PP2 (a Src-family kinase inhibitor) or small interfering RNA (siRNA) was c...更多

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