Multiple melanomas after treatment for Hodgkin lymphoma in a non-Dutch p16-Leiden mutation carrier with 2 MC1R high-risk variants.

Adina Figl,Ranjit K Thirumaran,Selma Ugurel,Andreas Gast,Kari Hemminki,Rajiv Kumar,Dirk Schadendorf

Archives of dermatology（2007）

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摘要

This study shows the variability of the penetrance of the CDKN2A Leiden mutation within the same family, which could be due to genetic or exogenous factors.

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