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Kindlin-2 Is An Essential Component Of Intercalated Discs And Is Required For Vertebrate Cardiac Structure And Function

CIRCULATION RESEARCH, no. 4 (2008): 423-431

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Integrins and proteins that associate with integrins are implicated in normal cardiac muscle function and development. Unc-112 is a cytoplasmic adaptor protein required for the proper establishment of integrin junctions in Caenorhabditis elegans muscle. A vertebrate homolog of unc-112, kindlin-2, is an integrin-binding protein that is exp...更多

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