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Efficient Parallel and Out of Core Algorithms for Constructing Large Bi-directed de Bruijn Graphs

BMC Bioinformatics, no. 1 (2010): 560

Cited: 73|Views42
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Abstract

Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly problem fall into two broad categories -- based on the data structures which they employ. The first class uses an overlap/string graph and the second type uses a de Bruijn graph....More

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