Preparation of Ultra-fine Particles of Acyclovir Using Rapid Expansion of Supercritical Solution

Fine Chemical Intermediates, pp. 65-68, 2011.

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Keywords:
ACVCO2ultra-fine particleRESS

Abstract:

This work was on the preparation of ultra-fine particles of acyclovir(ACV) in rapid expansion of supercritical solution(RESS).The solubility of ACV in supercritical CO2 was measured and effects of operation conditions on the size of ACV particles were investigated.It was found that ACV had poor solubility in SCF-CO2 and the value increase...More

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ZH超临界流体快速膨胀法制备超细阿昔洛韦粒子
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