Two-step N-acylindazole to N-alkylindazole reduction. Further synthetic studies on the serotonergic agonist AL-34662

Raymond E. Conrow,Pete Delgado,W. Dennis Dean,Gary R. Callen,Scott V. Plummer

Tetrahedron Letters（2008）

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摘要

The two-step method avoids C–N bond cleavage, which predominates under typical metal hydride reduction conditions. This opens a new route to regiocontrolled formation of N1-alkylindazoles.

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