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Therapy With Gastric Acidity Inhibitors Increases the Risk of Acute Gastroenteritis and Community- Acquired Pneumonia in Children

PEDIATRICS, no. 5.0 (2010): E817-E820

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OBJECTIVE. Gastric acidity ( GA) inhibitors, including histamine-2 receptor antagonists ( H-2 blockers) and proton pump inhibitors ( PPIs), are the mainstay of gastroesophageal reflux disease ( GERD) treatment. A prolonged GA inhibitor-induced hypochlorhydria has been suggested as a risk factor for severe gastrointestinal infections. In a...更多

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