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Tegaserod Does Not Significantly Affect The Pharmacokinetics Of Dextromethorphan In Healthy Subjects.

Jyoti Kalbag,Elizabeth Migoya,Stuart Osborne,Kenneth Lasseter, Manuel Pinto,James F. McLeod

GASTROENTEROLOGY（2000）

Cited 10|Views16
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Abstract
Background: There has been no study of the effects of suppository insertion on the parameters of the recto-anal inhibitory reflex (RAIR).We analyzed this effect in patients with different anorectal disorders.Methods: Eleven constipated and II incontinent patients underwent manometry and rectal compliance studies before and after rectal suppository insertion.
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Key words
dextromethorphan,pharmacokinetics
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