Plasma Hdl In Non-Insulin-Dependent Diabetes And The Effect Of Various Types Of Treatment

High density lipoprotein was studied in a group of non-insulin-dependent diabetics in relation to treatment with the hypoglycaemic sulphonylureas and biguanides. The effect of these drugs on hyperlipidaemia was also studied. HDL cholesterol (HDL-C) was reduced in all the diabetics, with no differences between the three groups studied:--diet-treated, SU-treated and biguanide-treated. The SU-treated group had lower cholesterol and triglycerides than the non-treated group. Biguanide treatment only affected the triglycerides level, but the difference from the non-treated group was not significant.