Diagnosis and therapy of primary lung diffuse large B cell lymphoma: a case report

Objective We studied the diagnosis and therapy of primary lung diffuse large B cell lymphoma (DLBCL). Methods Analysis the clinical manifestations, pathologic character and immunohistochemical character of one lung diffuse B cell lymphoma patent. Results In visual observation, it’s a gray irregular lobulated mass, section was gray, fish-like, and number of necrotic foci. Observed under the microscope, subepithelial respiratory center oocyte-like cells diffuse proliferative, infiltration in lung tissue. Immunohistochemistry: CD20 (+), CD79α (+), CD3 (−), CD45RO (−), PCK (−). Conclusion Diffuse large B cell lymphoma is the most common subtype in non-Hodgkin lymphoma, but the primary lung diffuse large B cell lymphoma is rare. This disease is lack of typical clinical manifestations, so easily misdiagnosed. The diagnosis of diffuse large B cell lymphoma should be based on pathology and immunohistochemistry.