Human immunoglobulin VH and VK repertoire revealed by in situ hybridization.

MOLECULAR IMMUNOLOGY, no. 9 (1990): 935-940

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We report in this paper the first analysis of the expression pattern of Ig VH and VK families in human adult normal peripheral B lymphocytes, by in situ hybridization using specific VH1 to VH6 and VK1 to VK4 probes, which cover the known human V gene families reported to date. The major families were VH3 and VK1, with the respective gradi...更多

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