CS 262 : Lecture 8 Notes Whole Genome Shotgun
msra(2002)
摘要
The motivation for sequencing genomes is rather direct. According to the central dogma of biology, elements of the genome are translated via several mechanisms into the structure and function of organisms. But in order to study genomes, we must first sequence them. Whole Genome Shotgun (WGS) is a successful method for sequencing genomes. This lecture we will discuss how WGS works, some of the challenges involved, solutions to these challenges.
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