Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat.

Yingxue Su,Wei Liu,Li Ma,Xiaochang Liu,Zhaochun Liu,Banghao Zhu

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY（2012）

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摘要

1. The aims of the present study were to explore the effects of: (i) scutellarin (Scu) on protein kinase C (PKC) translocation caused by diabetic conditions in diabetic rat thoracic aorta; and (ii) phorbol-12-myristate-13-acetate (PMA) treatment of cultured thoracic aortic smooth muscle cells.

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关键词

protein kinase C,scutellarin,thoracic aortic smooth muscle cells,translocation

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