Doxorubicin-loaded Zein in situ gel for interstitial chemotherapy

Chemical & pharmaceutical bulletin, Volume 60, Issue 10, 2012, Pages 1227-1233.

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Keywords:
microdialysislocal pharmacokinetic mathematical modellaser scanning confocal microscopyinterstitial chemotherapyin situ gel

Abstract:

A novel drug delivery system of doxorubicin (DOX)-loaded Zein in situ gel for interstitial chemotherapy was investigated in this study. The possible mechanisms of drug release were described according to morphological analysis by optical microscopy and scanning electronic microscope (SEM). In vitro and in vivo anti-tumor activity studies ...More

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