Effects of the root bark of Paeonia suffruticosa on mitochondria-mediated neuroprotection in an MPTP-induced model of Parkinson’s disease

Hyo Geun Kim,Gunhyuk Park,Ying Piao,Min Seo Kang,Youngmi Kim Pak,Seon-Pyo Hong,Myung Sook Oh

Food and Chemical Toxicology（2014）

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摘要

•MCE has anti-parkinsonian effect in vivo.•MCE rescues movement impairment induced by MPTP.•MCE protects against MPTP-induced striatal dopaminergic neurnal loss.•MCE inhibits MPTP-induced striatal mitochondrial dysfunction.

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关键词

Paeonia suffruticosa,Parkinson’s disease,Mitochondria dysfunction,MPTP

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