Epithelial-mesenchymal transition (EMT) and its effect on microRNA expression in lung cancer A549 cells

Chinese Journal of Oncology, Volume 33, Issue 8, 2011, Pages 590-593.

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Keywords:
Epithelial-mesenchymal transitionLung cancer cell line A549 cellsMicro RNA

Abstract:

Objective: To investigate the effect of epithelial-mesenchymal transition (EMT) on the expression of microRNAs (miRNAs) in lung cancer A549 cells. Methods: Transforming growth factor beta-1 (TGF-β1) in different concentrations was used to induce EMT in lung cancer A549 cells. The morphological changes were observed under phase-contrast mi...More

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