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YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway.

Journal of hematology & oncology, no. 1 (2015): 39-39

被引用8|浏览10
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Novel-targeted therapies are in rapid development for the treatment of acute lymphoblastic leukemia (ALL) to overcome resistance and decrease toxicity. Survivin, a member of the inhibitor of apoptosis gene family and chromosome passenger complex, is critical in a variety of human cancers, including ALL. A well-established suppressor of su...更多

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