Prognostic Value of CTNNB1 Gene Mutation in Primary Sporadic Aggressive Fibromatosis

Danique L. M. van Broekhoven,Cornelis Verhoef,Dirk J. Grünhagen,Joost M. H. H. van Gorp,Michael A. den Bakker,John W. J. Hinrichs,Carmen M. A. de Voijs,Thijs van Dalen

Annals of Surgical Oncology（2015）

引用 93|浏览25

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摘要

Aggressive fibromatosis (AF) comprises tumors with a varying biological behavior. Genetic tumor characteristics may be predictive of recurrence; hence, the prognostic value of three specific mutations on the CTNNB1 gene was evaluated in relation to known clinicopathologic risk factors in patients with primary, sporadic AF.

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关键词

Clinicopathologic Factor,Complete Tumor Resection,T41A Mutation,Aggressive Fibromatosis,CTNNB1 Mutation

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