Ultrasonography-guided multidrug stratification interventional therapy for cesarean scar pregnancy

Purpose To explore the clinical value of ultrasonography-guided multidrug stratification interventional therapy for cesarean scar pregnancy (CSP). Methods Aspiration of gestational sac fluid, injection of methotrexate in the sac, injection of homeostatic agent and pituitrin in the uterine muscle layer, and injection of triple anti-inflammatory drugs around the uterus in 12 patients with CSP. The lesion volume, serum β-hCG level, and blood flow were observed. Results The mean β-hCG level continued to decrease posttreatment, and the greatest reduction occurred in week 1. The mean number of days needed for serum β-hCG values to decrease to normal level was 39.1 ± 10.1 days. Mass volumes reduced and the mean number of days for the masses to disappear was 24.6 ± 14.1 days. The blood flow around the lesions continued to decrease. Conclusions Ultrasonography-guided multidrug interventional therapy for CSP is a new, safe, effective, minimally invasive method.