A 345 µW Multi-Sensor Biomedical SoC With Bio-Impedance, 3-Channel ECG, Motion Artifact Reduction, and Integrated DSP

This paper presents a MUlti-SEnsor biomedical IC (MUSEIC). It features a high-performance, low-power analog front-end (AFE) and fully integrated DSP. The AFE has three biopotential readouts, one bio-impedance readout, and support for general-purpose analog sensors The biopotential readout channels can handle large differential electrode offsets ( ±400 mV), achieve high input impedance ( >500 M Ω), low noise ( 620 nVrms in 150 Hz), and large CMRR ( >110 dB) without relying on trimming while consuming only 31 μW/channel. In addition, fully integrated real-time motion artifact reduction, based on simultaneous electrode-tissue impedance measurement, with feedback to the analog domain is supported. The bio-impedance readout with pseudo-sine current generator achieves a resolution of 9.8 m Ω/ √Hz while consuming just 58 μW/channel. The DSP has a general purpose ARM Cortex M0 processor and an HW accelerator optimized for energy-efficient execution of various biomedical signal processing algorithms achieving 10 × or more energy savings in vector multiply-accumulate executions.