Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays.

Darrell E Singer,Noah Kiwanuka,David Serwadda,Fred Nalugoda,Linda Hird,Jamie Bulken-Hoover,Godfrey Kigozi,Jennifer A Malia,Eva K Calero,Warren Sateren,Merlin L Robb,Fred Wabwire-Mangen,Maria Wawer,Ronald H Gray,Nelson Sewankambo,Deborah L Birx,Nelson L Michael

JOURNAL OF CLINICAL MICROBIOLOGY（2005）

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摘要

We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

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关键词

viral load,confidence intervals,algorithms,confidence interval

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