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Neutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor model.

JOURNAL OF CLINICAL INVESTIGATION, no. 4 (2010): 1151-1164

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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Abstract

Angiogenesis is a hallmark of malignant neoplasias, as the formation of new blood vessels is required for tumors to acquire oxygen and nutrients essential for their continued growth and metastasis. However, the signaling pathways leading to tumor vascularization are not fully understood. Here, using a transplantable mouse tumor model, we ...More

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