3,3 '-Diindolylmethane Is A Novel Mitochondrial H+-Atp Synthase Inhibitor That Can Induce P21(Cip1/Waf1) Expression By Induction Of Oxidative Stress In Human Breast Cancer Cells

Epidemiologic evidence suggests that high dietary intake of Brassica vegetables, such as broccoli, cabbage, and Brussels sprouts, protects against tumorigenesis in multiple organs. 3,3'-Diindolylmethane, one of the active products derived from Brassica vegetables, is a promising antitumor agent. Previous studies in our laboratory showed t...更多