Pregnancy: tolerance and suppression of immune responses.

Anne Leber,Maria Laura Zenclussen,Ana Teles,Nadja Brachwitz,Pablo Casalis,Tarek El-Mousleh,Federico Jensen,Katja Woidacki,Ana Claudia Zenclussen

SUPPRESSION AND REGULATION OF IMMUNE RESPONSES: METHODS AND PROTOCOLS（2011）

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摘要

Presence of foreign tissue in a host's body would immediately lead to a strong immune response directed to destroy the alloantigens present in fetus and placenta. However, during pregnancy, the semiallogeneic fetus is allowed to grow within the maternal uterus due to multiple mechanisms of immune tolerance, which are discussed in this chapter.

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关键词

Pregnancy,Tolerance,Regulatory T cells,Dendritic cells,Heme oxygenase-1

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