On the physiological significance of tumor necrosis factor-alpha in the human amniotic fluid.

V. Covelli, M. Jaccarino,F. Massari, S. Jaccarino, I. Munno, M. Marinaro, A. Gesario,N. M. Pellegrino, E. Jirillo

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY（2008）

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摘要

Tumor Necrosis Factor (TNF)-alpha and Interleukin (IL)-1beta levels have been measured in 16 weeks gestation amniotic fluids and mother's sera. Detectable levels of TNF-alpha were found in amniotic fluids, while IL-1beta was absent. No cytokines were detected in mother's sera. The possible role of TNF-alpha as growth factor for fetal hematopoietic cells is discussed.

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关键词

tumor necrosis factor

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