Protein quantification at the single vesicle level reveals that a subset of synaptic vesicle proteins are trafficked with high precision

The Journal of neuroscience : the official journal of the Society for Neuroscience, Volume 31, Issue 4, 2011, Pages 1461-1470.

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Abstract:

Protein sorting represents a potential point of regulation in neurotransmission because it dictates the protein composition of synaptic vesicles, the organelle that mediates transmitter release. Although the average number of most vesicle proteins has been estimated using bulk biochemical approaches (Takamori et al., 2006), no information...More

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