Lack of association of small-colony-variant Staphylococcus aureus strains with long-term use of azithromycin in patients with cystic fibrosis.

Nicole Green,Jane L Burns,Nicole Mayer-Hamblett,Margaret Kloster,Larry C Lands,Michael Anstead,Felix Ratjen,Lisa Saiman

JOURNAL OF CLINICAL MICROBIOLOGY（2011）

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摘要

There are increasing reports of small-colony-variant (SCV) strains of Staphylococcus aureus in patients with cystic fibrosis (CF) ([4][1]). In CF, azithromycin has been associated with the emergence of hypermutable strains ([2][2]), which also have increased antimicrobial resistance ([1][3]). SCV

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